Abstract: Indoor-cross infection of pathogen in relative enclosed environment has been still a concern since the SARS and recent cases of influenza spreading by commercial international flights. It is proved that smallpox, measles, tuberculosis, SARS and seasonal influenza can be transmitted during commercial flights. The researchers investi-gate the pathogen transmission modes and transmission routes in air cabins, as this is a key for developing relevant control strategies. These pathogen transmission modes and routes include direct contact transmission, indirection contact transmission and airborne transmission. A variety of methods can be utilized to investigate the pathogen cross-infection inside air cabins, airborne transmission patterns and infection probability of passengers in economy class, first class and business class respectively. These methods mainly include experiments in laboratory, statistics methods, and finally the computational fluid dynamics method. This paper basically presents the meanings of the research on pathogen transmission in civil aircraft cabin. And then it dedicates the research methods of pathogen transmission in air cabins as well as the results and applications. Three different kinds of methods which are usually adopted are focused in third section of this paper, including experiments in laboratory, statistics methods, and finally the numerical simulations method. At the end of the paper, the discussions and conclusions are drawn.

Key words: air cabin environment, pathogen transmission, transmission routes, computational fluid dynamics, statistics analysis