Abstract: As a type of hi-tech weapon, hypersonic vehicle plays an important strategic role in national security and benefits. It has now become a research hotspot in the field of aerospace, and the competition is becoming increasingly fierce all over the world. Advanced material and structure design is a basic key technology to support the development of hypersonic vehicle. The strength of materials and structures in extremely severe service environments is still a key issue restricting the development of this type of aircraft. This paper reviews the structure strength problems and evolution characteristics in the field of hypersonic vehicles in the past few decades. Combined with the current vehicle model development demand and technology development trend, this paper analyzes the current situation and shortcomings of structure strength technology in supporting the development of hypersonic vehicles and discusses the new requirements, new characteristics and new methods of strength problems in this field in the future. Finally, the future development direction in the field of hypersonic vehicle structure strength is proposed after summarization.